1 00:00:11,660 --> 00:00:16,250 Welcome to the project, How Epidemics and based at the University of Oxford. 2 00:00:16,250 --> 00:00:21,770 My name is Erica Charters. I'm an associate professor in the history faculty at the University of Oxford. 3 00:00:21,770 --> 00:00:28,960 And I'm Kristen Highton. I'm an independent scholar based in Bethesda, Maryland, which is just outside Washington, D.C. 4 00:00:28,960 --> 00:00:36,230 So over the next few weeks, Christine and I will be interviewing a range of experts to answer the big question, how at the end? 5 00:00:36,230 --> 00:00:45,610 But before we do that here, we'd like to explain why we think this question is important and the broader historical context to the end of epidemics. 6 00:00:45,610 --> 00:00:54,280 This project in some ways had its origin way back in the spring of twenty twenty in what might now be seen as the early days of covid-19. 7 00:00:54,280 --> 00:00:57,880 When Christian asked what might seem like a simple question, 8 00:00:57,880 --> 00:01:05,440 how do epidemics and Christian to remember could really do so back in January of twenty twenty, 9 00:01:05,440 --> 00:01:09,970 when it became quite clear that code was not going to be just a local outbreak. 10 00:01:09,970 --> 00:01:19,030 I remember thinking, oh, I know how this goes, because as historians we think a lot about the origins and the spread of disease 11 00:01:19,030 --> 00:01:23,410 and the broad patterns of epidemic disease are generally quite similar. 12 00:01:23,410 --> 00:01:33,880 covid followed those patterns. But then in early summer, when talk turned to how the epidemic would end and then it was time for it to end, 13 00:01:33,880 --> 00:01:39,400 I realised that I really had no clear idea at all about how epidemics ended it, 14 00:01:39,400 --> 00:01:44,350 not even about plague, which is something that I've worked on for several years now. 15 00:01:44,350 --> 00:01:50,260 So that's when I wrote to you. And I think that's something we continue to find throughout the project. 16 00:01:50,260 --> 00:01:56,470 There's a lot of attention paid to the origin, to the cause of the outbreak of an epidemic and also, 17 00:01:56,470 --> 00:02:01,510 of course, to the unfolding of an epidemic, but very little to the process of ending. 18 00:02:01,510 --> 00:02:09,670 So how do we know an epidemic has ended? Who defines an ending and how do we measure and assess that an epidemic has ended? 19 00:02:09,670 --> 00:02:14,080 And how, therefore, do we know when we can return to normal life? 20 00:02:14,080 --> 00:02:22,270 Do we take our guidance from a mathematical model or from an international health organisation or from when other people around us, 21 00:02:22,270 --> 00:02:27,970 ordinary people, return to their regular patterns of living and of working? 22 00:02:27,970 --> 00:02:32,260 So for this project, we wanted to incorporate all of these different methodologies. 23 00:02:32,260 --> 00:02:38,500 That is these different ways of measuring. But measurement and assessment is not just about numbers. 24 00:02:38,500 --> 00:02:46,480 It can be just as useful to be able to understand how and why normal people return to normal cultural practises, 25 00:02:46,480 --> 00:02:53,500 as it can be to know exact numbers of cases of disease if we want to understand how an epidemic ends. 26 00:02:53,500 --> 00:03:01,600 So for this project, we've worked with a range of researchers, over 40 scholarly experts who all work on disease. 27 00:03:01,600 --> 00:03:06,310 This includes epidemiologists, mathematical modellers, biologists, 28 00:03:06,310 --> 00:03:14,770 but it also includes people who work in politics and development to analyse the role of disease and the impact of disease on society. 29 00:03:14,770 --> 00:03:21,980 It also includes experts such as philosophers who work to define our conceptual understanding of disease. 30 00:03:21,980 --> 00:03:29,020 All of these researchers and details on them and our interviews with them can be found on the project website. 31 00:03:29,020 --> 00:03:37,180 We designed the project in two phases. First, an essay to disentangle our questions from what historians usually think about and to talk 32 00:03:37,180 --> 00:03:42,580 about the importance of including these several different approaches and methodologies. 33 00:03:42,580 --> 00:03:49,330 And then we recruited scholars for a series of online workshops which are now producing a set of essays for print publication, 34 00:03:49,330 --> 00:03:58,480 as well as these interviews. I think what we found is that each scholarly discipline has a different way of understanding disease, 35 00:03:58,480 --> 00:04:02,170 and we're both historians, so we have our specific approach. 36 00:04:02,170 --> 00:04:11,080 So for me, as a historian of medicine, when I study disease in the past, I'm not only analysing disease as a biological phenomenon. 37 00:04:11,080 --> 00:04:12,220 That is on the one hand, 38 00:04:12,220 --> 00:04:20,350 I do incorporate our modern biological understandings of disease to say when I look at smallpox in the sixteen hundreds and the seventeen hundreds, 39 00:04:20,350 --> 00:04:28,030 I do look at how it's transmitted. It's rates of deaths, it's symptoms according to modern biological understandings and smallpox. 40 00:04:28,030 --> 00:04:32,260 But on the other hand, I also examine how those at the time understood. 41 00:04:32,260 --> 00:04:38,110 So within their medical understanding, but also within their social and cultural frameworks, 42 00:04:38,110 --> 00:04:42,700 people in the past have their own strategies for controlling and avoiding disease, 43 00:04:42,700 --> 00:04:47,500 as well as ways in which they lived alongside it and interpreted that. 44 00:04:47,500 --> 00:04:53,590 So in other words, historians see disease not as separate from society, but as part of it. 45 00:04:53,590 --> 00:04:59,650 So epidemics, for example, are not events that come down impact upon society. 46 00:04:59,650 --> 00:05:08,590 We historians don't consider epidemics as external to society as if they're are aliens coming from outer space and invading society. 47 00:05:08,590 --> 00:05:16,990 Instead, historians of medicine start from the position that epidemics like disease in general should be understood as part of society. 48 00:05:16,990 --> 00:05:21,250 So in this approach, disease is part of social and cultural frameworks. 49 00:05:21,250 --> 00:05:30,970 It highlights existing inequalities, for example, or reinforces social tensions and prejudices rather than creating them anew. 50 00:05:30,970 --> 00:05:41,920 So as a historian, I use disease as a way to analyse society as a whole, to reveal and understand the ways that societies function. 51 00:05:41,920 --> 00:05:46,390 Kristen, your research is really much more focussed on the history of measurement. 52 00:05:46,390 --> 00:05:54,100 How does this relate to the disease? So I'm mostly interested in the history of science and mathematics as well as disease 53 00:05:54,100 --> 00:06:00,180 and medicine in that recently has meant looking at metrics and systems of records. 54 00:06:00,180 --> 00:06:08,500 So what gets measured, how it gets measured, and then how those data are used and understood by various individuals and communities. 55 00:06:08,500 --> 00:06:16,780 And that, too, is a great lens to look at a society or community more generally, especially interested right now in how communities, 56 00:06:16,780 --> 00:06:25,180 so scientists and practitioners as well as society at large come to any kind of consensus about what to measure, 57 00:06:25,180 --> 00:06:30,280 what measures and standards are appropriate and what to make. 58 00:06:30,280 --> 00:06:36,250 Of course, dealing with an epidemic produces a whole lot more metrics and records of its own, especially nowadays. 59 00:06:36,250 --> 00:06:45,550 But epidemics also strain and even upend ordinary recordkeeping in the kind of social order is expected to support. 60 00:06:45,550 --> 00:06:52,780 I think epidemics are very interesting as a historical phenomenon, but I also work on the history of disease more broadly, 61 00:06:52,780 --> 00:06:59,500 and one of the points that's important for me to stress is that we need to think about what is an epidemic. 62 00:06:59,500 --> 00:07:05,950 The opposite of an epidemic is not lack of disease, but rather what we might call endemic disease. 63 00:07:05,950 --> 00:07:12,490 I was really struck by this image of the global history through pandemics that's been circulated through 64 00:07:12,490 --> 00:07:19,600 covid-19 in which the all of the history of the world is represented by these balls that are each pandemics. 65 00:07:19,600 --> 00:07:25,240 And the size of the ball is meant to kind of represent the number of people killed by each disease. 66 00:07:25,240 --> 00:07:32,830 This image and what it's telling us about the histories, in some ways, this notion that there's these empty spaces between these balls. 67 00:07:32,830 --> 00:07:37,450 But what's important for me as a historian of disease is to remember that these empty spaces, 68 00:07:37,450 --> 00:07:41,170 those periods of history are not periods in which there was no disease, 69 00:07:41,170 --> 00:07:46,870 but actually in which the world was still full of disease, which is full of what we call endemic disease. 70 00:07:46,870 --> 00:07:52,390 So today in the West, the diseases that we know, such as tuberculosis, heart disease, 71 00:07:52,390 --> 00:07:59,830 diabetes and influenza and these endemic diseases can be just as fatal as epidemic disease. 72 00:07:59,830 --> 00:08:06,550 Cumulatively, for example, endemic disease kills an astonishingly high number of people in a normal year, 73 00:08:06,550 --> 00:08:10,360 and endemic disease is not defined by the type of disease. 74 00:08:10,360 --> 00:08:14,140 Right. So influenza is usually an endemic disease, 75 00:08:14,140 --> 00:08:22,360 but it can become an epidemic disease if suddenly there are higher rates than normal or it brings up in an unusual season. 76 00:08:22,360 --> 00:08:29,230 So epidemics are about diseases that are novel or unusual for that time or that place. 77 00:08:29,230 --> 00:08:39,130 For example, in the 17th and 18th centuries, smallpox in England and in Europe was considered endemic, almost normal in cities. 78 00:08:39,130 --> 00:08:45,470 But it was an epidemic disease, something that you would run away from when it appeared in the countryside. 79 00:08:45,470 --> 00:08:52,780 But if we step back and if we move to a global a global framework, so we say stand in the perspective of the Americas, 80 00:08:52,780 --> 00:09:01,840 there are smallpox was an epidemic disease everywhere, but by contrast, considered as endemic to all of Asia and Europe. 81 00:09:01,840 --> 00:09:07,030 So this notion of what is an epidemic, what is a problem disease, what is a crisis? 82 00:09:07,030 --> 00:09:11,800 Disease relies on an underlying category of endemic disease. 83 00:09:11,800 --> 00:09:15,190 What is normal or acceptable rates of disease? 84 00:09:15,190 --> 00:09:24,640 Just as current discussions, discussions of covid-19 are framed around questions of what is excess death or excess mortality. 85 00:09:24,640 --> 00:09:34,390 And I think we've discovered. Through this project, the disease most often returns to endemic levels at the end of an epidemic as well, 86 00:09:34,390 --> 00:09:41,250 with our experience with effective vaccinations, we tend to think about disease eradication as the end goal. 87 00:09:41,250 --> 00:09:45,660 But that's not usually the way even modern epidemics and. 88 00:09:45,660 --> 00:09:54,900 So, Erica, how do epidemics a question that we hope to find more answers as we develop more research on this project, 89 00:09:54,900 --> 00:10:04,260 but I think what we found so far is that one way of thinking about the end of an epidemic is that it's when society's attention turns elsewhere. 90 00:10:04,260 --> 00:10:08,190 An epidemic is a crisis. It's not just a biological crisis, though. 91 00:10:08,190 --> 00:10:15,570 It's also a political crisis and economic crisis and a social crisis, as we're witnessing now with covid-19. 92 00:10:15,570 --> 00:10:21,720 So what we've both found in our research is how the process of the end of an epidemic often isn't recorded. 93 00:10:21,720 --> 00:10:30,240 Less attention is paid to it precisely because for those who are living through an epidemic, it ends when they can return back to their normal lives. 94 00:10:30,240 --> 00:10:39,210 And so that's when they stop discussing the outbreak, stop discussing the disease, stop paying attention to it, and so stop keeping records. 95 00:10:39,210 --> 00:10:45,690 But what we've also found in our research is that most often, of course, this doesn't mean that the disease has actually ended. 96 00:10:45,690 --> 00:10:50,820 It might disappear for those who are writing records, but that doesn't mean it's gone. 97 00:10:50,820 --> 00:10:59,160 It often instead moves to say other parts of the world, as we've seen with HIV AIDS, which began as an epidemic for the entire world, 98 00:10:59,160 --> 00:11:03,280 but now has become much more of a problem disease in what we call the global 99 00:11:03,280 --> 00:11:09,300 south or a disease might become part of regular cycles or waves of disease, 100 00:11:09,300 --> 00:11:14,970 as we've seen with influenza. So it transforms into an endemic disease. 101 00:11:14,970 --> 00:11:23,580 One of the most interesting things I've learnt is how differently different groups define what the end actually is. 102 00:11:23,580 --> 00:11:30,510 So it's partly, as you say, that we as humans are attuned most to what matters to us and what is going on around us. 103 00:11:30,510 --> 00:11:37,080 And we pay less attention to what's going on somewhere else or people that we don't know. 104 00:11:37,080 --> 00:11:42,510 But in order to understand the full picture, the epidemic and especially pandemic itself, 105 00:11:42,510 --> 00:11:47,540 we have to do some work in order to pull together more points of view. 106 00:11:47,540 --> 00:11:54,720 And part of that is just access to sound information, but it's also that the end is defined differently by the various communities, 107 00:11:54,720 --> 00:12:02,120 both within a society and around the world, and also by the various groups that contribute to bringing that and about. 108 00:12:02,120 --> 00:12:09,720 So we have lots of narratives to look at, lots of ways of making sense of both the data and the experience in hand. 109 00:12:09,720 --> 00:12:18,270 The broad statistics that we're used to looking at as a general public typically see things that a more general level. 110 00:12:18,270 --> 00:12:24,060 So they talk about society as a whole and don't have that kind of specificity. 111 00:12:24,060 --> 00:12:31,380 They gloss over the fact that some communities continue to struggle with the disease long after the epidemic is declared over. 112 00:12:31,380 --> 00:12:37,140 And then by the same token, in international contexts, if there is outside aid coming in, 113 00:12:37,140 --> 00:12:44,310 those outside organisations may decide that things are good enough that they need to move on to the next big crisis, 114 00:12:44,310 --> 00:12:51,710 leaving the people in the society basically to manage on their own. 115 00:12:51,710 --> 00:12:57,560 But that difference in in endings helps make clear why these stories about how 116 00:12:57,560 --> 00:13:04,610 epidemics and epidemics end are so ragged that the endings themselves are different. 117 00:13:04,610 --> 00:13:10,190 And although the fact that they all exist in the same reality means that they interact, 118 00:13:10,190 --> 00:13:16,920 they reflect the interests and ends of the people who are putting the narratives together. 119 00:13:16,920 --> 00:13:21,990 I think this point about the rag and the rag admits of the ends of academics is very 120 00:13:21,990 --> 00:13:28,320 important epidemics and at different times for different groups within one society, 121 00:13:28,320 --> 00:13:31,140 but also within regions and across the world, 122 00:13:31,140 --> 00:13:41,760 which is precisely why studying the ends of epidemics gives us such useful insight into societies and how they work or even how they don't work. 123 00:13:41,760 --> 00:13:43,950 So thank you very much for joining us today. 124 00:13:43,950 --> 00:13:51,540 We have a number of fascinating interviews lined up over the next few weeks, including with an epidemiologist who's working on the end of malaria, 125 00:13:51,540 --> 00:13:59,400 a professor of politics who studies cholera in Africa, and a social historian who researches the history of cholera in England. 126 00:13:59,400 --> 00:14:07,510 We hope you will join us in interviewing the other researchers on the project as we work together to explain how epidemics and. 127 00:14:07,510 --> 00:14:17,086 Thank you.