1 00:00:04,090 --> 00:00:09,610 Welcome to this podcast brought to you by Sleep and the Rhythms of Life Project at the University of Oxford. 2 00:00:10,180 --> 00:00:15,070 I'm Sally Shuttleworth, and I'm here to introduce our two guests who will be in conversation today. 3 00:00:15,640 --> 00:00:22,299 First, Russell Foster, who's professor of circadian neuroscience at the University of Oxford and author of the bestselling 4 00:00:22,300 --> 00:00:27,880 book Lifetime The New Science of the Body Clock and How It Can Revolutionise Your Health. 5 00:00:28,750 --> 00:00:37,240 And second, Ian Ritchie, a world renowned architect, artist and author whose work begins with light as the primary material of architecture. 6 00:00:39,910 --> 00:00:47,260 Sleep occupies about one third of our lives, and since the pandemic has been a particular focus of concern and indeed anxiety, 7 00:00:47,560 --> 00:00:52,480 as so many people have reported, disrupted sleep or problems of getting to sleep in the first place. 8 00:00:55,290 --> 00:00:58,770 The focus of our conversation today is perhaps an unusual one. 9 00:00:59,040 --> 00:01:03,450 Sleep In relation to light and architecture, Russell and Ian, 10 00:01:03,720 --> 00:01:10,590 how can a neuroscientist and an architect help us to understand the world of sleep and the rhythms that govern our lives? 11 00:01:11,400 --> 00:01:19,670 And what can you both learn from each other? Well in and I have been working together for quite some time. 12 00:01:19,670 --> 00:01:27,590 The first project was the Sainsbury Welcome Centre in London and I think we met around a table. 13 00:01:27,920 --> 00:01:32,600 And of course I'm a slight geek and I wanted to ask, you know, what's your favourite building? 14 00:01:33,050 --> 00:01:42,230 And he said, the Crystal Palace. And I was completely gobsmacked because that's my favourite building and I was obsessed with it because 15 00:01:42,230 --> 00:01:48,050 of this great temple of glass allowing natural light in to illuminate these extraordinary objects. 16 00:01:48,470 --> 00:01:53,660 Interesting, Russell. My first recollection of meeting you was at the Royal Society. 17 00:01:53,660 --> 00:02:03,800 You said, What is your favourite colour? Oh, and I replied, 481 nanometres, to which you said you're one nanometre out. 18 00:02:04,190 --> 00:02:05,840 The brain probably doesn't know it. 19 00:02:06,290 --> 00:02:15,199 And of course the significance of 480 nanometres is the wavelength of the maximum sensitivity of the photoreceptors that we discovered in the eye, 20 00:02:15,200 --> 00:02:18,500 which are regulating the biological clock and a number of other things. 21 00:02:20,180 --> 00:02:28,700 As you and I have discussed and there's been this revolution over the past 20 years or so in understanding not only how circadian rhythms tick, 22 00:02:29,300 --> 00:02:34,970 but how they're regulated by light. So we have this internal day, the circadian clock, 23 00:02:34,970 --> 00:02:41,420 which is fine tuning every aspect of our physiology and behaviour to the very demands of the natural light dog cycle. 24 00:02:41,420 --> 00:02:49,540 The 24 hour day. And of course, it's the eye that detects this light, dark cycle and sets the internal clock. 25 00:02:49,930 --> 00:02:55,600 But what's turned out to be fascinating is that it's not the visual cells of the eye, the rods and cones, 26 00:02:55,870 --> 00:03:04,810 but it's this third photoreceptor we discovered which is maximally sensitive to blue light blue light of around 480 nanometres or so. 27 00:03:05,560 --> 00:03:09,070 But it's more than just the colour and the intensity. 28 00:03:09,070 --> 00:03:17,290 What we're also discovering is the rate of change of the light, the time of light exposure, the duration of light exposure. 29 00:03:17,470 --> 00:03:21,010 And this will change and of sensitivities will change as we age. 30 00:03:21,310 --> 00:03:27,790 And there's even arguments that the circadian clock changes its sensitivity with different illness states. 31 00:03:27,940 --> 00:03:34,540 So, for example, in mental illness, there's a suggestion that in some groups they might be more sensitive to light and 32 00:03:34,540 --> 00:03:38,560 therefore have their circadian rhythms shifted all over the place and in some cases, 33 00:03:38,710 --> 00:03:39,910 less sensitive to light. 34 00:03:40,180 --> 00:03:48,580 And so this emerging information, what's exciting is we can start to think about how we can incorporate these new discoveries into building design. 35 00:03:50,740 --> 00:04:03,640 So I think that any built space needs to embrace our biology so that an environment optimises vision but also optimises alertness. 36 00:04:03,850 --> 00:04:09,850 So it's bright enough for alertness. It's bright enough for regulating the clock and therefore the sleep wake systems. 37 00:04:10,630 --> 00:04:17,590 I think it's interesting that daylight and windows for architects was more about the view out of the window. 38 00:04:18,730 --> 00:04:27,400 Rather than the amount of light coming in. And there are many examples in the 5060s through the PFI period and building hospitals 39 00:04:27,400 --> 00:04:33,760 where windows were placed relatively high to the sleeping position in their ward, 40 00:04:34,690 --> 00:04:38,710 so that when the patient sits up to look out the window, they can't see anything. 41 00:04:41,030 --> 00:04:47,899 If one approaches an example of a ward and you've got patients who are requiring sleep at different times, 42 00:04:47,900 --> 00:04:58,040 possibly because of having had operations, recovery periods, mental state How does an architect go about designing the lighting for a board? 43 00:04:58,910 --> 00:05:03,410 What would be your first move as an architect? Talk to Russell Foster. 44 00:05:05,120 --> 00:05:11,270 If we don't get the light right, you know, build spaces, whether they be domestic spaces or workspaces, 45 00:05:11,660 --> 00:05:17,210 then the consequences of a disrupted circadian and sleep system are severe. 46 00:05:17,870 --> 00:05:23,879 So short term disruption can involve fluctuations in mood, irritability, loss of empathy. 47 00:05:23,880 --> 00:05:32,240 You fail to pick up the social signals from friends, family, work, colleagues, risk taking and doing stupid and unreflective things. 48 00:05:32,630 --> 00:05:40,310 So all of those are really quite, quite profound changes in our emotional responses or ability to focus. 49 00:05:40,670 --> 00:05:43,610 It's very interesting. People say it's all about multitasking. It isn't. 50 00:05:43,620 --> 00:05:48,000 It's about actually focusing upon all the variables, options that you've got to. 51 00:05:48,030 --> 00:05:53,719 And focusing is very difficult if you're not getting enough sleep, attention, concentration, decision making, 52 00:05:53,720 --> 00:05:59,450 creativity, productivity, all of these things are hugely affected if you're not getting the right sleep. 53 00:06:00,020 --> 00:06:04,610 And then long term and this is primarily within the nightshift community. 54 00:06:04,760 --> 00:06:09,110 But there's a great example where I don't think there's any sensible lighting design. 55 00:06:09,410 --> 00:06:14,120 What we know is there's increased cardiovascular disease, altered stress responses, 56 00:06:14,420 --> 00:06:19,030 type two diabetes, low immunity, high rates of infection, high rates of cancer. 57 00:06:19,040 --> 00:06:24,349 And of course, the big one, depression and psychosis by not getting the right sort of sleep, 58 00:06:24,350 --> 00:06:28,880 which is profoundly influenced by light in our domestic workspaces. 59 00:06:29,060 --> 00:06:35,240 So not getting sleep is so much more than the inconvenience of feeling tired at the wrong time. 60 00:06:35,510 --> 00:06:37,460 It impacts upon our global health. 61 00:06:37,880 --> 00:06:46,490 And that's why a dialogue between architects and neuroscientists is so very important, because it's fundamental to human health. 62 00:06:49,970 --> 00:06:55,790 I think it's a cultural issue as well between different cultures based on where you are on the earth. 63 00:06:56,760 --> 00:07:00,320 As you go towards the equator, artificial light is whiter. 64 00:07:01,350 --> 00:07:05,610 The further north you go to the Nordic countries, it's more like a candle. 65 00:07:06,600 --> 00:07:12,000 They go yellow spectrum. And I think that has something to do with. 66 00:07:13,450 --> 00:07:21,249 The environment, the overall environment you're in, in terms of a light environment and it's embedded in somewhere into one's culture, 67 00:07:21,250 --> 00:07:25,870 in one's body is not as simple as saying, well, if we do have water here in, 68 00:07:25,870 --> 00:07:30,219 say, Caribbean, then you apply the same word, design a light design to one. 69 00:07:30,220 --> 00:07:34,660 In Helsinki. You can have the right answer. You won't. Yes, I think that's a very important point. 70 00:07:34,930 --> 00:07:40,389 And just to emphasise, of course, a light environment is immensely dynamic changes, 71 00:07:40,390 --> 00:07:45,630 intensity changes in colour, in wavelength changes in the position of the sun in the sky. 72 00:07:45,640 --> 00:07:53,770 These are all critical factors. And what the circadian and sleep systems need to do is extract time of day information from that. 73 00:07:54,160 --> 00:07:58,870 And because the stimulus is so complicated, we have to think. 74 00:07:58,870 --> 00:08:06,580 I think our first principle would be that the sensory systems detecting that complex light environment are also going to be pretty sophisticated, 75 00:08:06,790 --> 00:08:14,859 which gets us back to do we know enough about the light input systems to make clear judgements about human centric lighting? 76 00:08:14,860 --> 00:08:22,089 And I don't think we do. But the problem is on the basis of what we do know, shouldn't we start to do something now? 77 00:08:22,090 --> 00:08:30,070 And so I think that's a bit of a challenge is how far can architects take this information and embedded in buildings when the story is incomplete? 78 00:08:30,400 --> 00:08:33,490 Well, I think we're absolutely right to actually go for it. 79 00:08:34,330 --> 00:08:42,820 Without an authoritarian viewpoint, because the more buildings that we're designing with the sensitivity, even if it's incomplete, 80 00:08:43,270 --> 00:08:50,620 we will get the measure of its success or not, because we have lots of people out there who are the guinea pigs carrying into these buildings. 81 00:08:50,950 --> 00:08:56,530 And if we were to institute a sort of an understanding, a regime of assessment, then we might get somewhere. 82 00:08:56,760 --> 00:09:02,260 Mm hmm. Absolutely. The timing of light exposure, of course, is critically important. 83 00:09:02,620 --> 00:09:09,910 And the way that you can incorporate that into building design, I think, is going to be really the exciting vanguard in the next decade. 84 00:09:13,440 --> 00:09:18,240 And so it's thinking about what light we need during the day in the workspace. 85 00:09:19,080 --> 00:09:23,010 But of course, I suppose buildings are used increasingly over 24 seven, 86 00:09:23,370 --> 00:09:28,860 and so just restricting them to a lighting regime for the daytime would also be naive. 87 00:09:30,150 --> 00:09:35,370 The 24 seven well that we've landed ourselves with is totally contrary to our biology 88 00:09:35,370 --> 00:09:39,420 because we have light when we don't expect it or the body doesn't expect it. 89 00:09:40,600 --> 00:09:47,530 I like the idea of the ceiling being a Zen space, a space of total neutrality, not even a fire detector up there. 90 00:09:48,100 --> 00:09:51,490 So you can actually look at a part of a room in the space or in. 91 00:09:52,430 --> 00:09:56,180 And feel no obligation to be like silence, visual silence. 92 00:09:56,990 --> 00:10:01,280 And that we've managed to succeed to do in a big project in Malta. 93 00:10:02,150 --> 00:10:07,670 We have opening windows. We don't have air conditioning. We've used the sun to design the building. 94 00:10:09,110 --> 00:10:14,300 And the buildings to shade each other. So it shows that if you can get the right daylight level. 95 00:10:15,220 --> 00:10:21,280 You get a new type of feeling in the office space. You don't need a suspended saying you don't like coming from the ceiling. 96 00:10:21,790 --> 00:10:27,130 And at night, in the evening, we project on to it from the wall or from the columns. 97 00:10:27,550 --> 00:10:31,510 So there's nothing up there other than a beautiful, diffused light level. 98 00:10:32,440 --> 00:10:38,320 That's a very interesting point, because essentially what our built spaces have done is detach us from a natural environment. 99 00:10:38,330 --> 00:10:42,310 And of course, what I think you want to do is reconnect us with our natural. 100 00:10:42,520 --> 00:10:47,650 Yeah. And light is the first part of that. For an architect, this is the first material we use. 101 00:10:47,830 --> 00:10:53,980 And I think the more we learn about the science of sleep and circadian rhythms and the way that light interacts with these systems, 102 00:10:54,400 --> 00:10:57,880 the more that can inform advanced architectural design. 103 00:10:58,540 --> 00:11:08,290 We're moving away from the fact that sleep is a luxury and an indulgence, and lack of sleep is a socio economic issue. 104 00:11:08,500 --> 00:11:13,120 And when we were studying 10 to 13, 14 year olds, we asked the question. 105 00:11:14,370 --> 00:11:18,450 Does anybody share your sleeping space? The question we didn't ask is, do you have a bed? 106 00:11:19,110 --> 00:11:21,149 And as a result of these discussions, 107 00:11:21,150 --> 00:11:28,740 we realised that many of these children were sleeping on the family's sofa while the television was going on and the parents were there. 108 00:11:29,070 --> 00:11:36,960 And the people who were doing night shift work and are chronically tired, the children who are failing at school because they're chronically tired. 109 00:11:37,380 --> 00:11:44,430 And I don't think we've paid enough attention to the fact that deprivation of sleep is a socioeconomic issue, 110 00:11:44,430 --> 00:11:47,700 and indeed it's something that architecture could address. 111 00:11:50,310 --> 00:11:53,160 Thanks very much to Russell Foster and Ian Ritchie. 112 00:11:53,760 --> 00:11:59,940 This was the first episode of a new podcast brought to you by Sleep and the Rhythms of Life project at the University of Oxford. 113 00:12:00,540 --> 00:12:04,230 The producer Ruth Abrahams from Feast Collective Productions. 114 00:12:04,860 --> 00:12:09,210 Music by Madeleine Morris. Thanks for listening and goodbye.